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| Status |
Public on Jun 18, 2018 |
| Title |
miRNA expression data from multilineage differentiation of hiPSC |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
We built a comprehensive miRNA expression atlas for multilineage comparison by differentiating induced PSC (iPSC) into three lineages representatively derived from the three germ layers and profiling the dynamic miRNA expression by microarray.
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| Overall design |
The hiPSC line iBC 1.2 was induced to differentiate into representative lineages of the three germ layers, namely, hepatocytes for endoderm (HD), nephron progenitors for mesoderm (KD), and neural progenitors for ectoderm (ND), respectively. miRNA expression profiling was performed using small RNA microarrays. Each lineage differentiation including eight samples with replicates for four time-points (day 0, 3, 6, 10) were collected and profiled.
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| Contributor(s) |
Li L, Chan WY, Cheung HH |
| Citation(s) |
29941943 |
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| Submission date |
Apr 18, 2017 |
| Last update date |
Sep 18, 2018 |
| Contact name |
Lu Li |
| E-mail(s) |
greenpearll0804@gmail.com
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| Phone |
323-442-0277
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| Organization name |
University of Southern California
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| Department |
School of Pharmacy
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| Street address |
Room 706, 1985 Zonal Ave
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| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90089 |
| Country |
USA |
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| Platforms (1) |
| GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
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| Samples (24)
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| GSM2583573 |
HD 3, biological rep-2 |
| GSM2583574 |
HD 6, biological rep-1 |
| GSM2583575 |
HD 6, biological rep-2 |
| GSM2583576 |
HD 10, biological rep-1 |
| GSM2583577 |
HD 10, biological rep-2 |
| GSM2583578 |
KD 0, biological rep-1 |
| GSM2583579 |
KD 0, biological rep-2 |
| GSM2583580 |
KD 3, biological rep-1 |
| GSM2583581 |
KD 3, biological rep-2 |
| GSM2583582 |
KD 6, biological rep-1 |
| GSM2583583 |
KD 6, biological rep-2 |
| GSM2583584 |
KD 10, biological rep-1 |
| GSM2583585 |
KD 10, biological rep-2 |
| GSM2583586 |
ND 0, biological rep-1 |
| GSM2583587 |
ND 0, biological rep-2 |
| GSM2583588 |
ND 3, biological rep-1 |
| GSM2583589 |
ND 3, biological rep-2 |
| GSM2583590 |
ND 6, biological rep-1 |
| GSM2583591 |
ND 6, biological rep-2 |
| GSM2583592 |
ND 10, biological rep-1 |
| GSM2583593 |
ND 10, biological rep-2 |
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| Relations |
| BioProject |
PRJNA383449 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE97952_RAW.tar |
19.8 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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