|
| Status |
Public on Jan 23, 2018 |
| Title |
Differential miRNA and mRNA Expression in Immortalized Human Keratinocytes (HaCaT) after Low Arsenic Exposure [miRNA] |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
Determining the miRNA and mRNA expression profiles in HaCaT cells at early and late stages of arsenite exposure to reveal early and late changes in the HaCaT cells transformation process.
|
| |
|
| Overall design |
4 biological rereplicates of HaCaT cells exposed to 100 nM sodium arsenite and unexposed HaCaT cells (Control)
|
| |
|
| Contributor(s) |
Al-Eryani L, Waigel S, Jenkins S, Arumugam V, States JC |
| Citation(s) |
29319823, 28595984 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P20 RR016481 |
KY IDeA Networks of Biomedical Research Excellence |
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION |
NIGEL G.F. COOPER |
| P20 GM103482 |
Molecular Targets COBRE |
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION |
Donald M. Miller |
| P30 GM106396 |
Molecular Targets Phase III CoBRE |
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION |
Donald M. Miller |
|
| |
| Submission date |
Mar 31, 2017 |
| Last update date |
Aug 13, 2019 |
| Contact name |
J. Christopher States |
| E-mail(s) |
jcstates@louisville.edu
|
| Organization name |
University of Louisville
|
| Department |
Department of Pharmacology & Toxicology
|
| Street address |
505 S. Hancock St., Rm 304
|
| City |
Louisville |
| State/province |
KY |
| ZIP/Postal code |
40202 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
|
| Samples (18)
|
| GSM2561453 |
HaCaT cells-exposed to 100 nM sodium arsenite for 3 weeks-replicate 1 |
| GSM2561454 |
HaCaT cells-exposed to 100 nM sodium arsenite for 3 weeks-replicate 2 |
| GSM2561455 |
HaCaT cells-exposed to 100 nM sodium arsenite for 3 weeks-replicate 3 |
| GSM2561456 |
HaCaT cells-exposed to 100 nM sodium arsenite for 3 weeks-replicate 4 |
| GSM2561457 |
As-TM cells; HaCaT cells-exposed to 100 nM sodium arsenite for 7 weeks-replicate 1 |
| GSM2561458 |
HaCaT cells-exposed to 100 nM sodium arsenite for 7 weeks-replicate 2 |
| GSM2561459 |
HaCaT cells-exposed to 100 nM sodium arsenite for 7 weeks-replicate 3 |
| GSM2561460 |
HaCaT cells-exposed to 100 nM sodium arsenite for 7 weeks-replicate 4 |
| GSM2561461 |
HaCaT cells-exposed to 100 nM sodium arsenite for 28 weeks-replicate 1 |
| GSM2561462 |
HaCaT cells-unexposed sodium arsenite maintained for 3 weeks-replicate 1 |
| GSM2561463 |
HaCaT cells-unexposed sodium arsenite maintained for 3 weeks-replicate 2 |
| GSM2561464 |
HaCaT cells-unexposed sodium arsenite maintained for 3 weeks-replicate 3 |
| GSM2561465 |
HaCaT cells-unexposed sodium arsenite maintained for 3 weeks-replicate 4 |
| GSM2561466 |
HaCaT cells-unexposed sodium arsenite maintained for 7 weeks-replicate 1 |
| GSM2561467 |
HaCaT cells-unexposed sodium arsenite maintained for 7 weeks-replicate 2 |
| GSM2561468 |
HaCaT cells-unexposed sodium arsenite maintained for 7 weeks-replicate 3 |
| GSM2561469 |
HaCaT cells-unexposed sodium arsenite maintained for 7 weeks-replicate 4 |
| GSM2561470 |
Matching control of As-TM cells; HaCaT cells-unexposed sodium arsenite maintained for 28 weeks-replicate 1 |
|
| This SubSeries is part of SuperSeries: |
| GSE97306 |
Differential miRNA and mRNA Expression in Immortalized Human Keratinocytes (HaCaT) after Low Arsenic Exposure |
|
| Relations |
| BioProject |
PRJNA381232 |
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