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Series GSE94543 Query DataSets for GSE94543
Status Public on Mar 22, 2017
Title Next Generation Sequencing analysis using splenic DCs freshly isolated from Wild Type and TBK1-DKO mice
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary In this experiment, we analyzed the gene expression profile of WT and TBK1-deficient splenic DCs by RNA sequencing based on three independent samples. The results revealed significant alterations in the expression of a number of genes, most notably the enhanced expression of a large subset of IFN-responsive genes in the TBK1-deficient DCs.
Overall design Fresh splenic DC mRNA profiles of 8-week old wild type (WT) and TBK1-DKO mice were generated by deep sequencing, in triplicate
Contributor(s) Xiao Y, Zou Q, Xie X, Manyam G, Zhang L, Sun S
Citation(s) 28356390
Submission date Feb 06, 2017
Last update date May 15, 2019
Contact name Shao-cong Sun
Organization name MD Anderson Cancer Center
Department Immunology
Lab Dr. Sun's Lab
Street address 7455 Fannin St.
City Houston
State/province TX
ZIP/Postal code 77054
Country USA
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (6)
GSM2477942 KO1
GSM2477943 KO2
GSM2477944 KO3
BioProject PRJNA371452
SRA SRP098902

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE94543_RAW.tar 610.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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