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Series GSE94509 Query DataSets for GSE94509
Status Public on Aug 20, 2019
Title Genome-wide CRISPR knockout to screen for essential targets for HCC cell growth
Organism Homo sapiens
Experiment type Other
Summary We performed genome-wide functional knockout screens using GECKOv2 library to identify essential growth targets in two hepatocellular carcinoma (HCC) cell lines, HCCLM3 and SNU449. We compared the gRNA present at the end of 10 passages (End Point) vs. that at Time zero in these two cell lines separately then overlap for common targets.
 
Overall design End Point vs. Time Zero.
 
Contributor(s) Wang Y, Hui KM
Citation(s) 31022357
Submission date Feb 03, 2017
Last update date Aug 20, 2019
Contact name Yu Wang
E-mail(s) wangyu81@gmail.com
Phone 64368352
Organization name National University of Singapore
Department Biochemistry
Lab Liver Cancer Functional Genomics
Street address 11 Hospital Drive
City Singapore
ZIP/Postal code 169610
Country Singapore
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (5)
GSM2477201 GECKOv2library
GSM2477202 HCCLM3TimeZero
GSM2477203 HCCLM3EndPoint
Relations
BioProject PRJNA370012
SRA SRP098832

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE94509_Count.txt.gz 1.9 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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