Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
Summary
We performed several extensive phenotypic, genomic, and transcriptomic analyses in an effort to discern the biological differences between normal breast cancer cell lines and breast cancer cells with a mutation in the ESR1 Ligand Binding Domain.
Overall design
ER ChIP-seq and mRNA-seq of Several MCF7 and T47D Cell lines
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