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| Status |
Public on Jan 01, 2018 |
| Title |
Modulation of EMP2 in HEC1A cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Previous studies have suggested that overexpression of the oncogenic protein epithelial membrane protein-2 (EMP2) correlates with endometrial carcinoma progression and ultimately poor survival from disease. To understand the role of EMP2 in the etiology of disease, gene analysis was performed to show transcripts that are reciprocally regulated by EMP2 levels. In particular, EMP2 expression correlates with and helps regulate the expression of several cancer stem cell associated markers including aldehyde dehydrogenase 1 (ALDH1).
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| Overall design |
Cells which overexpress EMP2 or express a shRNA knockdown (Sh KD) vector were used.
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| Contributor(s) |
Wadehra M |
| Citation missing |
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| |
| Submission date |
Dec 23, 2016 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Madhuri Wadehra |
| E-mail(s) |
mwadehra@mednet.ucla.edu
|
| Phone |
310-825-1590
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| Organization name |
UCLA
|
| Department |
Pathology and Lab Medicine
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| Street address |
675 Charles Young Dr. South/ 4726 MRL
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| City |
LA |
| State/province |
CA |
| ZIP/Postal code |
90095 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA358714 |
