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Series GSE92842 Query DataSets for GSE92842
Status Public on Nov 22, 2017
Title Single cell mRNAseq of Olfactory Epithelium and Neurog1-eGFP+ progenitors
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Single cell mRNAseq maps a global landscape of transcriptomes in uninjured tissue, showing clear transitions from neuronally fated progenitors to mature neurons and other mature cell types. Comparison with injured Neurog1-eGFP+ cells shows a dedifferentiation of cells towards a multipotent stem cell transcriptome.
 
Overall design Single cell transcriptomic analysis using Fluidigm C1 Autoprep of uninjured, unsorted mouse olfactory epithelium as a reference, compared to Neurog1-eGFP+ progenitors sorted from uninjured, 5 and 14 days post olfactory bulbectomy, and OMP-eGFP+ mature sensory neurons post olfactory bulbectomy
 
Contributor(s) Schwob JE, Lin B
Citation(s) 29174332
Submission date Dec 22, 2016
Last update date May 15, 2019
Contact name Brian Lin
E-mail(s) brian.lin@tufts.edu
Organization name Tufts University
Department DMCB
Street address 136 Harrison Avenue
City Boston
State/province MA
ZIP/Postal code 02111
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (469)
GSM2437953 q1_Uninjured olfactory epithelium
GSM2437954 q2_Uninjured olfactory epithelium
GSM2437955 q3_5dpOBX injured olfactory epithelium
Relations
BioProject PRJNA358604
SRA SRP095557

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE92842_20161214_scRNAseq_Count.csv.gz 5.2 Mb (ftp)(http) CSV
GSE92842_20161214_scRNAseq_FPKM.csv.gz 5.4 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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