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Series GSE89206 Query DataSets for GSE89206
Status Public on Jun 16, 2017
Title ZEB1-regulated inflammatory phenotype in breast cancer cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary This SuperSeries is composed of the SubSeries listed below.
Zinc finger E-box binding protein 1 (ZEB1) and ZEB2 induce epithelial-mesenchymal transition (EMT) and cancer progression. However, little is known about global picture of transcriptional regulation by ZEB1 and ZEB2. Here we identified an inflammatory phenotype regulated by ZEB1 using chromatin immunoprecipitation-sequencing (ChIP-seq) and RNA-sequencing (RNA-seq) in basal type breast cancer cells, followed by gene set enrichment analysis (GSEA) of ZEB1-bound genes.
Overall design Refer to individual Series
Citation(s) 28618162
Submission date Oct 26, 2016
Last update date Jul 25, 2021
Contact name Daizo Koinuma
Organization name University of Tokyo
Department Molecular Pathology
Street address Hongo 7-3-1, Bunkyo-ku
City Tokyo
ZIP/Postal code 113-0033
Country Japan
Platforms (1)
GPL17303 Ion Torrent Proton (Homo sapiens)
Samples (12)
GSM2360622 ZEB1 ChIP-seq, MDA-231-D cells
GSM2360623 ZEB1 ChIP-seq, Hs578T cells
GSM2360627 RNA-seq_si Negative control
This SuperSeries is composed of the following SubSeries:
GSE89203 ZEB1 binding sites in TGF-beta-stimulated MDA-231-D and Hs578T basal type breast cancer cell lines [ChIP-seq]
GSE89205 RNA-sequencing in TGF-beta treated MDA-231-D cells transfected with ZEB1/ZEB2 siRNAs [RNA-seq]
GSE98270 ZEB1 binding sites in TGF-beta-stimulated MCF7 breast cancer cell line
BioProject PRJNA350678

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Supplementary file Size Download File type/resource
GSE89206_RAW.tar 1.4 Gb (http)(custom) TAR (of BED, BW)
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