NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE8763 Query DataSets for GSE8763
Status Public on Aug 08, 2008
Title Global gene expression profile of small intestine from wild-type and CFTR-knockout mice.
Organism Mus musculus
Experiment type Expression profiling by array
Summary The objective of this study was to identify changes in gene expression levels between wild-type and CFTR-knockout small intestine. CFTR-knockout mice (provided by Dr. Lane Clarke of the University of Missouri) were maintained on colyte.
Keywords: gene expression comparison
 
Overall design Four wild-type and four CFTR-knockout small intestinal RNA samples were compared. To facilitate statistical analysis and reduce affects of Cy3 and Cy5 labeling, comparison of two WT and two KO were repeated with a dye flip.
 
Contributor(s) Shull GE, Bradford EE
Citation(s) 19164484
Submission date Aug 13, 2007
Last update date Jan 18, 2013
Contact name Gary Shull
Organization name University of Cincinnati
Street address 231 Albert Sabin Way ML0524
City Cincinnati
State/province OH
ZIP/Postal code 45267
Country USA
 
Platforms (1)
GPL5738 Duke University Murine Operon v.3.0 spotted Array
Samples (1)
GSM217788 intestine_cysticfibrosis_1
Relations
BioProject PRJNA102043

Significantly Change Genes header descriptions
Oligo ID
Ensembl gene_id
Genbank
description
symbol
DF
avg intensity
KO / WT
log2(KO/WT)
p-value

Data table
Oligo ID Ensembl gene_id Genbank description symbol DF avg intensity KO / WT log2(KO/WT) p-value
M300014051 ENSMUSG00000042963 1 32 -10.52 -3.39 0.0002
M300007509 ENSMUSG00000030954 AK009661 glycoprotein 2 (zymogen granule membrane). [Source:RefSeq;Acc:NM_025989] Gp2 2 160 -7.65 -2.93 0.0009
M300000555 ENSMUSG00000004415 BC075713 Collagen alpha 1(XXVI) chain precursor (EMI domain containing protein 2) (Emu2 protein) (Emilin and multimerindomain containing protein 2). [Source:Uniprot/SWISSPROT;Acc:Q91VF6] Emid2 2 142 -6.93 -2.79 0.0000
M200000038 ENSMUSG00000023034 BC004770 Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein). [Source:Uniprot/SWISSPROT;Acc:P12813] Nr4a1 1 444 -6.31 -2.66 0.0000
M200002600 ENSMUSG00000015971 AK017815 Actinrelated protein 8. [Source:Uniprot/SWISSPROT;Acc:Q8R2S9] Actr8 1 338 -5.62 -2.49 0.0000
M200000761 ENSMUSG00000058135 J04632 Glutathione Stransferase Mu 1 (EC 2.5.1.18) (GST classmu 1) (Glutathione Stransferase GT8.7) (pmGT10) (GST 11). [Source:Uniprot/SWISSPROT;Acc:P10649] Gstm1 3 2905 -5.51 -2.46 0.0008
M300018438 ENSMUSG00000063749 BC034249 ring finger protein 137 Rnf137 1 192 -5.16 -2.37 0.0000
M200009401 ENSMUSG00000025002 BC010824 cytochrome P450, family 2, subfamily c, polypeptide 55; cytochrome P450, 2c55. [Source:RefSeq;Acc:NM_028089] Cyp2c55 3 796 -4.87 -2.28 0.0002
M200013571 ENSMUSG00000052605 isochorismatase domain containing 2; RIKEN cDNA 0610042E07 gene NM_026158 3 316 -4.67 -2.22 0.0000
M300009146 ENSMUSG00000034110 AK083583 potassium channel tetramerisation domain containing 7. [Source:RefSeq;Acc:NM_172509] Kctd7 1 42 -4.46 -2.16 0.0016
M200003934 ENSMUSG00000003053 BC013895,D17674 Cytochrome P450 2C29 (EC 1.14.14.1) (CYPIIC29) (P450 MUT2) (Aldehyde oxygenase). [Source:Uniprot/SWISSPROT;Acc:Q64458] Cyp2c29 3 434 -4.44 -2.15 0.0020
M300013653 ENSMUSG00000042371 AK082798 Novel protein. [Source:Uniprot/SPTREMBL;Acc:Q5SWY8] 1 117 -4.36 -2.12 0.0002
M200003795 ENSMUSG00000025226 BC016499 Fbox only protein 37. [Source:RefSeq;Acc:NM_133694] Fbxl15 3 582 -4.23 -2.08 0.0000
M200009408 ENSMUSG00000020405 Gastrotropin (GT) (Ileal lipidbinding protein) (ILBP). [Source:Uniprot/SWISSPROT;Acc:P51162] Fabp6 3 2178 -3.78 -1.92 0.0023
M300004432 ENSMUSG00000025017 AF293806 phosphoinositide3kinase adaptor protein 1; B cell phosphoinositide 3kinase adaptor. [Source:RefSeq;Acc:NM_031376] Pik3ap1 1 201 -3.58 -1.84 0.0016
M300004004 ENSMUSG00000024230 cAMP responsive element modulator 2 363 -3.27 -1.71 0.0001
M200003519 ENSMUSG00000028836 BC013478,AK031425 solute carrier family 30 (zinc transporter), member 2 3 272 -3.15 -1.65 0.0004
M200002283 ENSMUSG00000027569 BC085320,AK005551 MRG-binding protein; RIKEN cDNA 1600027N09 gene CT20_MOUSE 1 185 -3.06 -1.61 0.0003
M200008281 ENSMUSG00000031340 AF189263 gammaaminobutyric acid (GABAA) receptor, subunit epsilon. [Source:RefSeq;Acc:NM_017369] Gabre 1 123 -2.99 -1.58 0.0034
M300011691 ENSMUSG00000054417 AB033414 Cytochrome P450 3A41 (EC 1.14.14.1). [Source:Uniprot/SWISSPROT;Acc:Q9JMA7] Cyp3a41 3 4730 -2.97 -1.57 0.0022

Total number of rows: 251

Table truncated, full table size 33 Kbytes.




Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE8763_RAW.tar 17.8 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table
| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap