|
| Status |
Public on Apr 05, 2017 |
| Title |
Genome-wide histone modification profiling in endometriosis cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We show that knocking down ARID1A in an immortalized endometriosis cell line leads to phenotypic changes in vitro. Additionally, we find strong increases in the active H3K27ac mark in promoter regions but decrease of H3K27ac at potential enhancers.
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| |
|
| Overall design |
Examination of 4 different histone modifications in endometriosis control and ARID1A knockdown cell lines.
|
| |
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| Contributor(s) |
Lakshminarasimhan R, Andreu-Vieyra C, Lawrenson K, Duymich CE, Gayther SA, Liang G, Jones PA |
| Citation(s) |
28483516 |
| Submission date |
Sep 12, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Ranjani Lakshminarasimhan |
| E-mail(s) |
ranjanil@usc.edu
|
| Phone |
3238650736
|
| Organization name |
University of Southern California
|
| Department |
Urology
|
| Lab |
Jones/Liang
|
| Street address |
1441 Eastlake ave NOR7336
|
| City |
Los Angeles |
| State/province |
California |
| ZIP/Postal code |
90033 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (18)
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| Relations |
| BioProject |
PRJNA342603 |
| SRA |
SRP089677 |
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