|
| Status |
Public on Feb 01, 2018 |
| Title |
Genes and mechanisms regulated by androgens as possible contributors to the male excess observed in autism [hNSCs] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We analyzed androgen receptor (AR) target genes on human neural stem cells (hNSCs) by ChIP-sequencing of AR IP after either DMSO (solvent), Testosterone 100nM, DHT 10 or 100nM 4 hours treatment in order to find the role of AR during brain development.
|
| |
|
| Overall design |
Examination of AR IP sequences after DMSO (1 technical replicate), Testosterone 100nM (AR agonist, 2 technical replicates), DHT 10nM (AR agonist, natural metabolite of testosterone, 2 technical replicates) or DHT 100nM treatment by deep sequencing using Illumina HiSeq 2500
|
| |
|
| Contributor(s) |
Quartier A, Jost B, Le Gras S, Piton A |
| Citation(s) |
29428674 |
| |
| Submission date |
Sep 06, 2016 |
| Last update date |
Dec 18, 2020 |
| Contact name |
Angélique Quartier |
| E-mail(s) |
a.quartier@inoviem.com
|
| Organization name |
IGBMC
|
| Street address |
1, rue Laurent Fries
|
| City |
Illkirch |
| ZIP/Postal code |
67400 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (10)
|
|
| This SubSeries is part of SuperSeries: |
| GSE86458 |
Genes and mechanisms regulated by androgens as possible contributors to the male excess observed in autism |
|
| Relations |
| BioProject |
PRJNA341957 |
| SRA |
SRP086624 |
Less...
More...