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Series GSE86356 Query DataSets for GSE86356
Status Public on Sep 29, 2016
Title Transcriptional profiling of Myotonic dystrophy muscle and heart
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Autopsy and biopsy muscle and heart tissue was collected from consented human subjects with and without confirmed myotonic dystrophy type 1, myotonic dystrophy type 2, or Duchenne muscular dystrophy. RNA was isolated for preparation of RNAseq libraries and sequenced on the Illumina platform.
 
Overall design 126 samples, comprising 103 distinct individuals, were sequenced. In some cases, several tissues from the same individual were obtained (the anonymized patient identifier can be used to link these). Samples were obtained from 4 different centers around the world (anonymized center identifiers can be used to track these).
 
Contributor(s) Wang ET, Treacy D, Wang TT, Estabrook J, Day J, Brook D, Thornton C, Cooper T, Housman DH, Burge CB
Citation missing Has this study been published? Please login to update or notify GEO.
NIH grant(s)
Grant ID Grant title Affiliation Name
RC2 HG005624 Deep Sequencing Analysis of mRNA Isoform Expression Changes in Myotonic Dystrophy MASSACHUSETTS INSTITUTE OF TECHNOLOGY Burge
DP5 OD017865 Ppst-transcriptional regulation of gene expression in neuromuscular disease: Post-transcriptional regulation of gene expression in neuromuscular disease UNIVERSITY OF FLORIDA Wang
Submission date Sep 01, 2016
Last update date Mar 20, 2019
Contact name Eric T Wang
Organization name University of Florida
Street address 2033 Mowry Rd
City Gainesville
State/province FL
ZIP/Postal code 32610
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (126)
GSM2309518 Bicep_DM1_1
GSM2309519 Bicep_DM1_2
GSM2309520 Bicep_DM1_3
Relations
BioProject PRJNA342787
SRA SRP089788

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE86356_DMseq_sample_converted_nonUTR_psi.txt.gz 11.5 Mb (ftp)(http) TXT
Raw data are available in SRA
Processed data is available on Series record

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