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| Status |
Public on Feb 01, 2017 |
| Title |
A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of gene expression in pathologically confirmed glioblastoma (GBM) samples. These data were used to test a classifier that was generated to distinguish GBM tumor samples with loss of neurofibromin 1 (NF1) function
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| |
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| Overall design |
Microarray analysis was performed on total RNA isolated from flash frozen GBM samples.
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| Contributor(s) |
Way GP, Allaway RJ, Barnard RA, Bouley SJ, O'Roak BJ, Fadul C, Sanchez Y, Greene CS |
| Citation(s) |
28166733 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 NS095411 |
Targeting Tumors with NF1 Loss |
DARTMOUTH COLLEGE |
Sanchez |
| P30 CA023108 |
Cancer Center Support Grant: Administration: CARRYOVER: Cancer Center Support Grant (CER Initiatives): Cancer Center Support Grant - Core Consolidation Supplement: Clinical Protical: DEVELOPMENTAL FUNDS: Development Funds: Developmental Funds: Immune: Miroarray Shared Resource: PROGRAM PLANNING AND EVALUATION: Planning & Evaluation: Planning and Evaluation: Protocal Specific: Research Program Directors: SENIOR LEADERSHIP |
DARTMOUTH COLLEGE |
Israel |
| UL1 TR001086 |
SYNERGY: The Dartmouth Center for clinical and Translational Science |
DARTMOUTH COLLEGE |
GREEN |
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| |
| Submission date |
Aug 01, 2016 |
| Last update date |
Oct 29, 2018 |
| Contact name |
Robert Allaway |
| Organization name |
Geisel School of Medicine
|
| Department |
Department of Molecular and Systems Biology
|
| Street address |
Vail 501A, 72 College St
|
| City |
Hanover |
| State/province |
New Hampshire |
| ZIP/Postal code |
03755 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA335999 |
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