|
| Status |
Public on Aug 05, 2016 |
| Title |
GATA-2 occupancy in Kasumi-3 cell line |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
GATA-2 is a master regulator of hematopoiesis which controls expression of multiple genes and is implicated in acute myeloid leukemia (AML). However, the molecular mechanism how GATA-2 deregulation causes leukemogenesis is still unclear. In this study, GATA-2 ChIP-squ analysis was conducted in Kasumi-3 AML cell line to identify GATA-2 target genes which play important roles in the pathogenesis of AML.
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| |
|
| Overall design |
ChIP with GATA-2 antibody was conducted in Kasumi-3 AML cell line and ChIP-seq profile was generated by deep sequencing.
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| Contributor(s) |
Katsumura K, Bresnick EH, Farnham PJ |
| Citation(s) |
27545880 |
| |
| Submission date |
Jul 25, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Kyle Hewitt |
| E-mail(s) |
KJHEWITT@WISC.EDU
|
| Organization name |
University of Wisconsin
|
| Street address |
1111 Highland Ave.
|
| City |
Madison |
| State/province |
Wisconsin |
| ZIP/Postal code |
53705 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL10999 |
Illumina Genome Analyzer IIx (Homo sapiens) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA331135 |
| SRA |
SRP079678 |
