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| Status |
Public on Jun 08, 2017 |
| Title |
Comparaison of left and right cervical motoneurons transcriptome |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Left and Right phrenic nerves, which innervate the left and right diaphragm muscles, exhibit different innervation patterns. This left/right (L/R) asymmetry is established at the onset of innervation by a developmental program that requires Nodal. Phenotype analysis suggests that the cervical motoneurons, which innervate the diaphragm, have a L/R imprint that contributes to set the L/R asymmetries of innervation.
We used microarray to analyze the expression profile of left and right cervical motoneurons before diaphragm innervation
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| Overall design |
Left and right cervical motoneurons pools were collected from E11.5 HB9::GFP mice embryos. Left and right pools were collected from the same sections to allow paired analysis. The three embryos were from the same litter to minimize expression changes due to variation of the developmental stages.
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| Contributor(s) |
Falk J, Bozon M, Castellani V, Rey C, Croze S, Lachuer J |
| Citation(s) |
28639940 |
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| Submission date |
Jul 25, 2016 |
| Last update date |
Jun 25, 2019 |
| Contact name |
joel lachuer |
| E-mail(s) |
lachuer@univ-lyon1.fr
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| Phone |
+33 664035058
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| Organization name |
university Lyon1
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| Lab |
Profilexpert platform
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| Street address |
8 avenue rockefeller
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| City |
Lyon |
| ZIP/Postal code |
69008 |
| Country |
France |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (6)
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| GSM2250155 |
Embryon 1 E11.5 , right motoneurons, biological repeat 1 |
| GSM2250156 |
Embryon 1 E11.5, left motoneurons, biological repeat 1 |
| GSM2250157 |
Embryon 2 E11.5, right motoneurons, biological repeat 2 |
| GSM2250158 |
Embryon 2 E11.5, left motoneurons, biological repeat 2 |
| GSM2250159 |
Embryon 3 E11.5, right motoneurons, biological repeat 3 |
| GSM2250160 |
Embryon 3 E11.5, left motoneurons, biological repeat 3 |
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| Relations |
| BioProject |
PRJNA331128 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE84778_RAW.tar |
23.9 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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