NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE84593 Query DataSets for GSE84593
Status Public on Mar 01, 2017
Title Regulation of KMT2D by PI(3)K/AKT signalling orchestrates oestrogen receptor mediated transcriptional activation in breast cancer [ChIP-seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We aim to elucidate the mechanisms of how PI3K inhibition is promoting oestrogen receptor (ER) activation and ER dependency in breast cancer.
 
Overall design Genome-wide analysis of ER, FOXA1 TF upon treatment with the PI3K inhibitor (BYL719).
 
Contributor(s) Toska E, Osmanbeyoglu H
Citation(s) 28336670
Submission date Jul 19, 2016
Last update date May 15, 2019
Contact name Hatice Ulku Osmanbeyoglu
Organization name University of Pittsburgh
Street address 5117 Centre Ave
City Pittsburgh
State/province PA
ZIP/Postal code 15213
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (10)
GSM2242425 Input BYL719
GSM2242426 ER ChIP-seq BYL719 1
GSM2242427 ER ChIP-seq BYL719 2
This SubSeries is part of SuperSeries:
GSE84594 Regulation of KMT2D by PI(3)K/AKT signalling orchestrates oestrogen receptor mediated transcriptional activation in breast cancer
Relations
BioProject PRJNA330542
SRA SRP078949

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE84593_RAW.tar 2.6 Gb (http)(custom) TAR (of BW)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap