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Status |
Public on Mar 01, 2017 |
Title |
Regulation of KMT2D by PI(3)K/AKT signalling orchestrates oestrogen receptor mediated transcriptional activation in breast cancer [ChIP-seq] |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
We aim to elucidate the mechanisms of how PI3K inhibition is promoting oestrogen receptor (ER) activation and ER dependency in breast cancer.
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Overall design |
Genome-wide analysis of ER, FOXA1 TF upon treatment with the PI3K inhibitor (BYL719).
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Contributor(s) |
Toska E, Osmanbeyoglu H |
Citation(s) |
28336670 |
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Submission date |
Jul 19, 2016 |
Last update date |
May 15, 2019 |
Contact name |
Hatice Ulku Osmanbeyoglu |
Organization name |
University of Pittsburgh
|
Street address |
5117 Centre Ave
|
City |
Pittsburgh |
State/province |
PA |
ZIP/Postal code |
15213 |
Country |
USA |
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Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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Samples (10)
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This SubSeries is part of SuperSeries: |
GSE84594 |
Regulation of KMT2D by PI(3)K/AKT signalling orchestrates oestrogen receptor mediated transcriptional activation in breast cancer |
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Relations |
BioProject |
PRJNA330542 |
SRA |
SRP078949 |