|
| Status |
Public on Mar 01, 2017 |
| Title |
Regulation of KMT2D by PI(3)K/AKT signalling orchestrates oestrogen receptor mediated transcriptional activation in breast cancer [ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We aim to elucidate the mechanisms of how PI3K inhibition is promoting oestrogen receptor (ER) activation and ER dependency in breast cancer.
|
| |
|
| Overall design |
Genome-wide analysis of ER, FOXA1 TF upon treatment with the PI3K inhibitor (BYL719).
|
| |
|
| Contributor(s) |
Toska E, Osmanbeyoglu H |
| Citation(s) |
28336670 |
| |
| Submission date |
Jul 19, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Hatice Ulku Osmanbeyoglu |
| Organization name |
University of Pittsburgh
|
| Street address |
5117 Centre Ave
|
| City |
Pittsburgh |
| State/province |
PA |
| ZIP/Postal code |
15213 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (10)
|
|
| This SubSeries is part of SuperSeries: |
| GSE84594 |
Regulation of KMT2D by PI(3)K/AKT signalling orchestrates oestrogen receptor mediated transcriptional activation in breast cancer |
|
| Relations |
| BioProject |
PRJNA330542 |
| SRA |
SRP078949 |
Less...
More...