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Series GSE83993 Query DataSets for GSE83993
Status Public on Mar 30, 2017
Title Allele-Specific Non-CG Methylation Marks Domains of Active Chromatin in Mouse Brain
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
Summary We examined genome-wide, base-resolution, allele-specific methylation and expression in the prefrontal cortex using a mouse model of deterministic X-inactivation, where the paternal allele was always inactivated. Our findings elucidate the role methylation may play in chromatin regulation under X-inactivation and genomic imprinting.
 
Overall design MethylC-seq, RNA-seq from the mouse frontal cortex
 
Contributor(s) Keown CL, Berletch JB, Castanon R, Nery JR, Disteche CM, Ecker JR, Mukamel EA
Citation(s) 28320934
NIH grant(s)
Grant ID Grant title Affiliation Name
R00 NS080911 Global cortical dynamics in sleep and general anesthesia THE REGENTS OF THE UNIV. OF CALIF., UNIV. OF CALIF., SAN DIEGO ERAN A MUKAMEL
Submission date Jul 04, 2016
Last update date May 15, 2019
Contact name Eran A Mukamel
E-mail emukamel@ucsd.edu
Organization name University of California-San Diego
Department Cognitive Science
Street address 9500 Gilman Dr.
City San Diego
State/province United States
ZIP/Postal code 92037
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (4)
GSM2224963 RNA-seq_prefrontal_ctx_rep1
GSM2224964 RNA-seq_prefrontal_ctx_rep2
GSM2224965 MethylC-seq_prefrontal_ctx_rep1
Relations
BioProject PRJNA327757
SRA SRP077875

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE83993_MethylC-seq_DMRs_methylpy.txt.gz 27.8 Kb (ftp)(http) TXT
GSE83993_RAW.tar 11.7 Gb (http)(custom) TAR (of BW, TAR, TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data is available on Series record

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