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| Status |
Public on Jun 29, 2016 |
| Title |
Expression data from KDM3A knockdown MDA-MB-231 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Breast cancer invasive growth, metastasis and therapeutic resistance affects the clinical ourcome. We explored the epigenetic mechanisms that control these process in breast cancer cell line, MDA-MB-231 by knocking down a lysine specific demethylase KDM3A
We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process.
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| Overall design |
Human breast cancer cell line MDA-MB-231 was infected with scramble or KDM3A shRNA. After selection, the cells were used for microarray analysis.
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| Contributor(s) |
Ramadoss S, Guo G, Wang C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 28, 2016 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Cun-Yu Wang |
| E-mail(s) |
cunywang@ucla.edu
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| Phone |
3108254607
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| Organization name |
UCLA School of Dentistry
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| Department |
Division of Oral Biology and Medicine
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| Lab |
Laboratory of Molecular Signaling
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| Street address |
10833 Le Conte Avenue
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| City |
Los Angeles |
| State/province |
California(CA) |
| ZIP/Postal code |
90095 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA327095 |
