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Series GSE81510 Query DataSets for GSE81510
Status Public on Mar 01, 2017
Title Glucocorticoid Receptor: MegaTrans Switching Mediates Repression of ERα-Regulated Transcriptional Program [ChIP-Seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The mechanisms underlying GR-dependent inhibition of ERα-regulated gene activation programs at the global genomic level have been poorly understood. We found the binding of GR in trans on ERα-activated enhancers results in gene and enhancer repression by disassembling the MegaTrans Complex.
 
Overall design All ChIP-Seq experiments were designed to elucidate the mechanism involving GR-mediated repression of ERα-Regulated Transcriptional Program
 
Contributor(s) Yang F, Ma Q
Citation(s) 28475868
Submission date May 17, 2016
Last update date May 15, 2019
Contact name Qi Ma
E-mail(s) q1ma@ucsd.edu
Organization name UCSD
Street address 9500 Gilman Dr,
City San Diego
ZIP/Postal code 92093
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (16)
GSM2154984 ChIP-Seq ERα plus ICI
GSM2154985 ChIP-Seq ERα plus ICI and Dex
GSM2154986 ChIP-Seq ERα plus E2
This SubSeries is part of SuperSeries:
GSE81512 Glucocorticoid Receptor: MegaTrans Switching Mediates Repression of ER?-Regulated Transcriptional Program
Relations
BioProject PRJNA321838
SRA SRP075269

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE81510_RAW.tar 2.6 Gb (http)(custom) TAR (of BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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