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Series GSE78845 Query DataSets for GSE78845
Status Public on Aug 28, 2016
Title Single cell transcriptome analysis of mouse thoracic sympathetic ganglia
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We explore the heterogeneity of mouse thoracic ganglia demonstrating the presence of an unexpected variety of cell-types and identify specialized populations of nipple- and pilo-erector muscle neurons. These neurons extend axonal projections and are born amongst other neurons during embryogenesis, but remain unspecialized until target organogenesis occurs postnatally. Target innervation and cell-type specification is coordinated by an intricate acquisition of unique combinations of growth factor receptors and the initiation of expression of concomitant ligands by the nascent erector muscles.
Overall design RNA-seq analysis of 298 single sympathetic neuronal cells from the mouse thoracic ganglion
Contributor(s) Furlan A, La Manno G, Linnarsson S, Ernfors P
Citation(s) 27571008
Submission date Mar 02, 2016
Last update date May 15, 2019
Contact name Sten Linnarsson
Organization name Karolinska Institutet
Department Medical Biochemistry and Biophysics
Lab Molecular Neurobiology
Street address Scheeles väg 1
City Stockholm
ZIP/Postal code 171 65
Country Sweden
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (298)
GSM2079127 1772099-104_A01
GSM2079128 1772099-104_A10
GSM2079129 1772099-104_F03
BioProject PRJNA314132
SRA SRP071085

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