|
| Status |
Public on Aug 28, 2016 |
| Title |
Single cell transcriptome analysis of mouse thoracic sympathetic ganglia |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We explore the heterogeneity of mouse thoracic ganglia demonstrating the presence of an unexpected variety of cell-types and identify specialized populations of nipple- and pilo-erector muscle neurons. These neurons extend axonal projections and are born amongst other neurons during embryogenesis, but remain unspecialized until target organogenesis occurs postnatally. Target innervation and cell-type specification is coordinated by an intricate acquisition of unique combinations of growth factor receptors and the initiation of expression of concomitant ligands by the nascent erector muscles.
|
| |
|
| Overall design |
RNA-seq analysis of 298 single sympathetic neuronal cells from the mouse thoracic ganglion
|
| |
|
| Contributor(s) |
Furlan A, La Manno G, Linnarsson S, Ernfors P |
| Citation(s) |
27571008 |
| |
| Submission date |
Mar 02, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Sten Linnarsson |
| Organization name |
Karolinska Institutet
|
| Department |
Medical Biochemistry and Biophysics
|
| Lab |
Molecular Neurobiology
|
| Street address |
Scheeles väg 1
|
| City |
Stockholm |
| ZIP/Postal code |
171 65 |
| Country |
Sweden |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (298)
|
|
| Relations |
| BioProject |
PRJNA314132 |
| SRA |
SRP071085 |
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