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| Status |
Public on Feb 25, 2017 |
| Title |
Changes in the erythroblast miRNA profile in the bone marrow of a Plasmodium vivax-infected patient |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Human studies of Plasmodium vivax in the bone marrow are scarce. Here, we present a detailed characterization of bone marrow aspirates taken from a P. vivax patient with high parasitaemia on admission and 42 days after treatment. Analysis of miRNAs related to erythropoiesis revealed a distinct series of differentially expressed miRNAs during infection compared to at convalescence. These results suggest that parasites in the bone marrow affect erythropoiesis.
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| Overall design |
Characterization of bone marrow aspirates taken from a P. vivax patient with high parasitaemia on admission and 42 days after treatment
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| Contributor(s) |
Raiol T, de Lacerda MV, del Portillo HA |
| Citation missing |
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| Submission date |
Feb 25, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Taina Raiol |
| E-mail(s) |
taina.raiol@fiocruz.br
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| Organization name |
Oswaldo Cruz Foundation - Fiocruz
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| Department |
Fiocruz Brasília (GEREB)
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| Street address |
Av. L3 Norte, Campus Universitário Darcy Ribeiro
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| City |
Brasília |
| State/province |
DF |
| ZIP/Postal code |
70.904-130 |
| Country |
Brazil |
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| Platforms (1) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA313197 |
| SRA |
SRP070834 |
