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| Status |
Public on Jan 01, 2017 |
| Title |
Microarray gene-expression profiles of 50 pancreatic tumors tissue from patients with pancreatic ductal adenocarcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
In order to identify biologically relevant tumor markers, and novel therapeutic target we have compared the tumor gene expression profiles of long (OS>=24 months,n=14) and short (OS <=7months, n=11) survival patients. Then we conducted Kaplan-Meier survival analysis using all the 50 samples listed here. The Affymetrix gene-expression data of these 50 samples were also included in the earlier submission by us as GEO accession number GSE62452.
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| Overall design |
We compared the gene expression profiles of long and short survival patients, significantly differentially expressed genes were subjected to Ingenuity Pathway Analysis (IPA). Significantly differentially expressed genes with 1.5 fold change were further analyzed by Coxregression Proportional harzard ratio.
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| |
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| Contributor(s) |
Hussain SP |
| Citation(s) |
27401251 |
| |
| Submission date |
Feb 23, 2016 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Perwez S Hussain |
| E-mail(s) |
hussainp@mail.nih.gov
|
| Phone |
301-402-3431
|
| Organization name |
National Cancer Institute
|
| Lab |
Laboratory of Human Carcinogenesis
|
| Street address |
37 Convent Drive, Building 37, Room3044B
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (50)
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| Relations |
| BioProject |
PRJNA312957 |
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