|
| Status |
Public on Apr 01, 2016 |
| Title |
Regulation of androgen receptor signaling by Oct1 recruitment in prostate cancer |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Prostate cancer is the most common cancer in men and AR downstream signalings promote prostate cancer cell proliferation. To investigate the AR signaling, we performed ChIP sequence analysis in AR-positive prostate cancer cell lines, LNCaP and VCaP. In addition, we also examined the effect of PI polyamide specificly inhibit Oct1 binding to AR occupied-regions.
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| |
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| Overall design |
ChIP sequence analysis of AR binding sites and epigenetic condition in two prostate cancer cells
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| |
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| Contributor(s) |
Takayama K, Inoue S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Feb 10, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Ken-ichi Takayama |
| Organization name |
Tokyo Metropolitan Institute of Gerontology
|
| Street address |
Sakaecho
|
| City |
Itabashi-ku |
| ZIP/Postal code |
173-0015 |
| Country |
Japan |
| |
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| Platforms (2) |
| GPL10999 |
Illumina Genome Analyzer IIx (Homo sapiens) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (21)
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| This SubSeries is part of SuperSeries: |
| GSE77771 |
Targeting Oct1 genomic function inhibits androgen receptor signaling and castration-resistant prostate cancer growth |
|
| Relations |
| BioProject |
PRJNA311511 |
| SRA |
SRP069854 |
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