|
| Status |
Public on Dec 06, 2017 |
| Title |
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export III |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To eliminate the possibility that for a particular gene the increased RNA level is an effect of enhanced transcription. We carried out ChIP-seq for RNAPII to compare transcription of mRNAs and lncRNAs in control, hRRP40 and hMTR4 knockdown cells. Among 15000 RNAPII binding peaks identified in these samples, only less than 50 peaks was significantly increased in hRRP40 or hMTR4 knockdown cells.
|
| |
|
| Overall design |
DNAs isolated from input and IP sample in control, hRRP40 or hMTR4 knockdown HeLa cells were generated by deep sequencing, using Illumina HiSeq 2000.
|
| |
|
| Contributor(s) |
Wu X, Li M |
| Citation(s) |
28801509 |
| |
| Submission date |
Feb 05, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Hong Cheng |
| E-mail(s) |
hcheng@sibcb.ac.cn
|
| Organization name |
Shanghai Institutes for Biological Sciences
|
| Department |
Shanghai Institute of Biochemistry and Cell Biology
|
| Lab |
StateKey Laboratory of Molecular Biology
|
| Street address |
320 YueYang Road
|
| City |
Shanghai |
| ZIP/Postal code |
200031 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE77641 |
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export |
|
| Relations |
| BioProject |
PRJNA311069 |
| SRA |
SRP069722 |
Less...
More...