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Series GSE7763 Query DataSets for GSE7763
Status Public on Jun 21, 2007
Title Using FlyAtlas to identify better Drosophila models of human disease
Organism Drosophila melanogaster
Experiment type Expression profiling by array
Summary A new online resource (flyatlas.org) provides the most comprehensive view yet of expression in multiple tissues of Drosophila. Meta-analysis of the data reveals that a significant fraction ofthe genome is expressed with great tissue specificity in the adult, demonstrating the need for the functional genomic community to embrace a wider range of functional phenotypes. Well-known developmental genes are often re-used in surprising tissues in the adult, suggesting new functions. The homologues of many human genetic disease loci show selective expression in Drosophila tissues with function analogous to the affected tissues in the cognate human disease, providing a useful filter for potential candidate genes.
 
Overall design FlyAtlas is composed of data so far covering 31 distinct adult and larval tissues with 4 replicates on run using Affymetrix Dros Genome 2 chips, and compared with a matched whole-fly sample. The resource is continuosly extended with the funding secured until 2010.
Web link http://flyatlas.org/
 
Contributor(s) Chintapalli VR, Wang J, Dow JA
Citation(s) 17534367
Submission date May 09, 2007
Last update date Aug 28, 2018
Contact name Jing Wang or Venkat Chintapalli
E-mail jw128h@udcf.gla.ac.uk, vrc1h@udcf.gla.ac.uk
Phone 0141 3306212
Fax 3304878
Organization name University of Glasgow
Department Molecular Genetics
Lab Dow/Davis lab
Street address Dumbarton Road
City Glasgow
State/province Scotland
ZIP/Postal code G11 6NU
Country United Kingdom
 
Platforms (1)
GPL1322 [Drosophila_2] Affymetrix Drosophila Genome 2.0 Array
Samples (136)
GSM188072 Adult Hind Gut biological rep1
GSM188073 Adult Hind Gut biological rep2
GSM188074 Adult Hind Gut biological rep3
Relations
BioProject PRJNA99895

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE7763_RAW.tar 292.6 Mb (http)(custom) TAR (of CEL, CHP, XML)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

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