|
| Status |
Public on Aug 01, 2017 |
| Title |
Genome-wide screening of HNF1b binding sites identifies transcriptional regulation of the Kir4.1/Kir5.1 potassium channel |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
chIP-seq was used to provide a genome-wide screening of transcription factor HNF1B binding sites to further elucidate its effect on cyst formation, diabetes and electrolyte handling in patients. A highly specific dataset for Hnf1b binding was constructed for an immortalized murine DCT cell line (mpkDCT4a).
|
| |
|
| Overall design |
1 transcription factor and 1 histone modification in 1 cell type
|
| |
|
| Contributor(s) |
Kompatscher A, de Baaij JH, Hoefnagels AP, Veenstra GJ, Bindels RJ, Hoenderop JG |
| Citation(s) |
28577853 |
| |
| Submission date |
Jan 29, 2016 |
| Last update date |
Feb 15, 2022 |
| Contact name |
Andreas Kompatscher |
| E-mail(s) |
Andreas.Kompatscher@radboudumc.nl
|
| Phone |
+31243617799
|
| Organization name |
Radboud Institute for Molecular Life Sciences
|
| Department |
Physiology
|
| Lab |
Ion transport
|
| Street address |
Geert Grooteplein Zuid 30
|
| City |
Nijmegen |
| State/province |
Gelderland |
| ZIP/Postal code |
6525 GA |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA310219 |
| SRA |
SRP069074 |
