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Series GSE77161 Query DataSets for GSE77161
Status Public on Mar 12, 2016
Title Mouse cortex transcriptome response to a wild type West Nile virus (WNV), New York 99 Strain, and mutant WNV-E218A viruses [WCT001_miRNA]
Organism Mus musculus
Experiment type Non-coding RNA profiling by array
Summary The purpose is to obtain samples for mRNA, miRNA, proteomics, lipidomics, metabolomics, and histopathology analysis in mouse cortex infected with wild-type West Nile virus (WNV; WNV-NY99 382), and mutant WNV-E218A (WNV-NY99 382 E218A 2 nt).
Overall design Mice were inoculated with WNV intracranially at a dose of 100 FFU. Infected samples were collected in quintuplet; time-matched mocks were collected in quintuplet in parallel with infected samples. Time points: 2 and 4 days post-infection. This study (WCT001) and GSE77160 (WCB001) are 1/4 of cortex and 1/2 of cerebellum from the same mice. Tissues from this experiment are matched to tissues from GSE77160 (WCB001). Infectivity (titer) and pathology are measured from the tissue in WCT001 (i.e., this experiment).
Contributor(s) Thackray L, Stratton K, Waters KM, Eisfeld AJ, Kawaoka Y
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Submission date Jan 24, 2016
Last update date Aug 31, 2016
Contact name Natalie Heller
Organization name PNNL
Street address 902 Battelle Blvd.
City Richland
ZIP/Postal code 99354
Country USA
Platforms (1)
GPL19970 Agilent-046065 Mouse_miRNA_V19.0_Microarray [Probe Name version]
Samples (30)
GSM2045146 WCT001_mock_2d_microRNA_1
GSM2045147 WCT001_mock_2d_microRNA_2
GSM2045148 WCT001_mock_2d_microRNA_3
This SubSeries is part of SuperSeries:
GSE65575 Modeling Host Responses to Understand Severe Human Virus Infections
BioProject PRJNA309680

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE77161_RAW.tar 91.4 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table

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