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Series GSE76418 Query DataSets for GSE76418
Status Public on Sep 26, 2016
Title lncRNA DINO ChIRPseq in DNA damaged U2OS cells
Organism Homo sapiens
Experiment type Other
Summary Examine the chormatin localization of DINO in DNA damaged human U2OS cells using DINO ChIRP-seq.
 
Overall design DINO is a DNA damage induced long noncoding RNA required for the transactivation of several p53-regulated genes. We examined the chormatin localization of DINO in DNA damaged human U2OS cells in order to determine whether DINO regulated gene expression by interacting with gene regulatory elements. We performed ChIRP with two independed probe sets (even and odd) according to previously published methods (Chu et al. 2011) . RNAse treated chromatin controls identify we utilized to confirm that DINO ChIRP recovery of DNA was indeed RNA dependent and not the result of direct DNA interaction by the probes.
 
Contributor(s) Schmitt A, Shen Y, Chang H
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Submission date Dec 30, 2015
Last update date May 15, 2019
Contact name Adam Schmitt
E-mail(s) amschmit@stanford.edu
Phone 650-736-0305
Fax 650-723-8762
Organization name Stanford University
Department Department of Dermatology
Lab Howard Y. Chang
Street address 269 Campus Drive
City Stanford
State/province CA
ZIP/Postal code 94305-5168
Country USA
 
Platforms (1)
GPL9115 Illumina Genome Analyzer II (Homo sapiens)
Samples (6)
GSM2011201 DINO_ChIRP_EVEN
GSM2011202 DINO_ChIRP_ODD
GSM2011203 DINO_ChIRP_RNase_EVEN
This SubSeries is part of SuperSeries:
GSE76420 LncRNA DINO guides DNA damage signaling
Relations
BioProject PRJNA307254
SRA SRP067918

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE76418_RAW.tar 7.1 Mb (http)(custom) TAR (of NARROWPEAK)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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