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Series GSE76303 Query DataSets for GSE76303
Status Public on Apr 11, 2017
Title Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary We analysed the effect on the genomic localisation of cohesin (Stag1 and Scc1) and CTCF in CTCF, Smc3 and Wapl single depleted as well as CTCF Wapl double depleted mouse embryonic fibroblasts. Furthermore, we addressed the effect of CTCF and Smc3 depletion on gene expression as measured by RNA-Seq and the transcriptional activity in CTCF and Wapl double depleted cells by GRO-Seq.
Overall design ChIP-Seq profiles of CTCF, H3K4me2, H3K9ac, Nipbl, Scc1, Stag1 in wild-type mouse embryonic fibroblasts (MEFs, E13.5d), CTCF, Smc3 and Wapl depleted or CTCF Wapl double depleted MEFs; mRNA-seq profiles of wild-type MEFs as well as CTCF and Smc3 depleted MEFs; GRO-seq profiles of wild-type MEFs as well as CTCF Wapl double depleted MEFs.
Contributor(s) Busslinger GA, van der Lelij P, Stocsits RR
Citation(s) 28424523
Submission date Dec 23, 2015
Last update date May 15, 2019
Contact name Roman R Stocsits
Organization name IMP - Research Institute of Molecular Pathology
Lab Jan-Michael Peters' Lab
Street address Campus-Vienna-Biocenter 1
City Vienna
ZIP/Postal code 1030
Country Austria
Platforms (3)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (103)
GSM1979724 Stag1 ChIP (Peters Lab ID: 14549)
GSM1979725 Stag1 ChIP (Peters Lab ID: 14954)
GSM1979726 Stag1 ChIP (Peters Lab ID: 14551)
BioProject PRJNA306857
SRA SRP067744

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE76303_12156+27721.wig.gz 456.1 Mb (ftp)(http) WIG
GSE76303_14549+14954.wig.gz 506.8 Mb (ftp)(http) WIG
GSE76303_14551+19587+26233.wig.gz 484.0 Mb (ftp)(http) WIG
GSE76303_16816+18867.wig.gz 575.3 Mb (ftp)(http) WIG
GSE76303_16818+18871.wig.gz 617.2 Mb (ftp)(http) WIG
GSE76303_16820+18868.wig.gz 588.9 Mb (ftp)(http) WIG
GSE76303_16822+18872.wig.gz 597.1 Mb (ftp)(http) WIG
GSE76303_16824+18873.wig.gz 601.1 Mb (ftp)(http) WIG
GSE76303_16826+18869.wig.gz 571.3 Mb (ftp)(http) WIG
GSE76303_16828+18870.wig.gz 580.6 Mb (ftp)(http) WIG
GSE76303_16830+18874.wig.gz 614.7 Mb (ftp)(http) WIG
GSE76303_19588+26234+27235.wig.gz 510.5 Mb (ftp)(http) WIG
GSE76303_19589+20318+26235.wig.gz 508.7 Mb (ftp)(http) WIG
GSE76303_19593.wig.gz 103.8 Mb (ftp)(http) WIG
GSE76303_20093+20105.wig.gz 508.4 Mb (ftp)(http) WIG
GSE76303_20094+20106.wig.gz 503.9 Mb (ftp)(http) WIG
GSE76303_20095+20319+27716.wig.gz 511.7 Mb (ftp)(http) WIG
GSE76303_20096+20320+27717.wig.gz 507.2 Mb (ftp)(http) WIG
GSE76303_22603.wig.gz 89.6 Mb (ftp)(http) WIG
GSE76303_26236+27237.wig.gz 495.4 Mb (ftp)(http) WIG
GSE76303_26238+27718.wig.gz 493.0 Mb (ftp)(http) WIG
GSE76303_27715.wig.gz 130.1 Mb (ftp)(http) WIG
GSE76303_29071.wig.gz 345.9 Mb (ftp)(http) WIG
GSE76303_29072.wig.gz 355.6 Mb (ftp)(http) WIG
GSE76303_29073.wig.gz 353.2 Mb (ftp)(http) WIG
GSE76303_29074.wig.gz 321.8 Mb (ftp)(http) WIG
GSE76303_29075.wig.gz 321.7 Mb (ftp)(http) WIG
GSE76303_29076.wig.gz 317.5 Mb (ftp)(http) WIG
GSE76303_29077.wig.gz 322.2 Mb (ftp)(http) WIG
GSE76303_29078.wig.gz 323.9 Mb (ftp)(http) WIG
GSE76303_29079.wig.gz 322.6 Mb (ftp)(http) WIG
GSE76303_32721.wig.gz 441.2 Mb (ftp)(http) WIG
GSE76303_32722.wig.gz 441.0 Mb (ftp)(http) WIG
GSE76303_32723.wig.gz 446.0 Mb (ftp)(http) WIG
GSE76303_32724.wig.gz 445.7 Mb (ftp)(http) WIG
GSE76303_9147+27719.wig.gz 422.7 Mb (ftp)(http) WIG
GSE76303_9149+27722.wig.gz 441.8 Mb (ftp)(http) WIG
GSE76303_RAW.tar 93.6 Mb (http)(custom) TAR (of WIG)
GSE76303_RPKM_serum_stimulation.txt.gz 466.3 Kb (ftp)(http) TXT
GSE76303_RPKM_values_RNA-seq.txt.gz 2.6 Mb (ftp)(http) TXT
GSE76303_TPM_GRO-Seq_Ctcf-Wapal-dKO.sort.txt.gz 571.3 Kb (ftp)(http) TXT
GSE76303_TPM_GRO-Seq_wildtype.sort.txt.gz 375.6 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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