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Series GSE75662 Query DataSets for GSE75662
Status Public on Dec 04, 2015
Title Effects of an adrA mutant on Salmonella enterica gene expression during root colonization
Organism Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S
Experiment type Expression profiling by array
Summary Increasing evidence indicates that despite exposure to harsh environmental stresses, Salmonella enterica successfully persists on plants, utilizing fresh produce as a vector to animal hosts. This study examined the mechanisms of S. enterica plant colonization, including the role of the diguanylate cyclase AdrA. Utilizing microarray analysis, we identified a new function for AdrA in the transcriptional regulation of colanic acid biosynthesis genes.
Overall design Changes in gene expression, comparing wildtype to an adrA mutant, were measured in planktonic bacterial cells after 24-hour incubation with alfalfa seeds. Two independent experiments were performed for each strain (wildtype and the adrA mutant).
Contributor(s) Cowles KN, Barak JD
Citation(s) 26655751
Submission date Dec 03, 2015
Last update date Mar 01, 2016
Contact name Kimberly Cowles
Organization name University of Wisconsin-Madison
Street address 1630 Linden Drive
City Madison
State/province WI
ZIP/Postal code 53706
Country USA
Platforms (1)
GPL21187 Agilent-048466 Salmonella Typhimurium 14028S (Se14028s) 8x60 array
Samples (4)
GSM1963013 Wildtype_24h_rep1
GSM1963014 Wildtype_24h_rep2
GSM1963015 adrA_24h_rep1
BioProject PRJNA304999

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE75662_RAW.tar 43.6 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table

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