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Series GSE74928 Query DataSets for GSE74928
Status Public on Mar 26, 2016
Title XX-650-23, an inhibitor of CREB-CBP interaction, effect on acute myeloid leukemia cell line
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary Analysis of acute myeloid leukemia KG1 cells treated with XX-650-23 (5 mM) for 12hrs. XX-650-23 inhibits proliferation of KG1 cells. Results provides insight into the molecular mechanisms underlying by the inhibitory activity of XX-650-23 on acute leukemia.
Overall design mRNA profiles of KG1 cells treated with XX-650-23 were generated by deep sequencing.
CREB genome binding profiles of KG1 cells treated with XX-650-23 were generated by deep sequencing.
Contributor(s) Mitton B, Chae H, Ferrari R, Sakamoto KM
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Submission date Nov 12, 2015
Last update date May 15, 2019
Contact name Kathleen M Sakamoto
Organization name Stanford University
Department Pediatrics
Street address CCSR 1215C, 235 Campus Drive
City Stanford
State/province California
ZIP/Postal code 94305-5162
Country USA
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (8)
GSM1937937 DMSO rep1
GSM1937938 DMSO rep2
GSM1937939 XX-650-23 rep1
BioProject PRJNA301935
SRA SRP066087

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Supplementary file Size Download File type/resource
GSE74928_RAW.tar 230.0 Kb (http)(custom) TAR (of BED)
GSE74928_XX_RNAseq_rawCounts.txt.gz 185.5 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
Processed data provided as supplementary file

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