|
| Status |
Public on Nov 16, 2015 |
| Title |
Reduced insulin production relieves endoplasmic reticulum stress and induces beta-cell proliferation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We define the effects of reduced insulin production in beta-cells from tamoxifen-treated Ins1-/-:Ins2f/f:Pdx1CreERT:mTmG mice studied at a time point when insulin production was reduced by ~50%.
|
| |
|
| Overall design |
Examination of the transcriptome of adult pancreatic islets from mice with acute Ins2 gene knockout out on an Ins1 null background
|
| |
|
| Contributor(s) |
Johnson JD |
| Citation(s) |
26626461 |
| |
| Submission date |
Oct 16, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
James Daniel Johnson |
| E-mail(s) |
James.D.Johnson@ubc.ca
|
| Phone |
16048227187
|
| Organization name |
University of British Columbia
|
| Department |
Cellular and Physiological Sciences
|
| Lab |
5358 Life Sciences Institutes
|
| Street address |
2350 Health Sciences Mall
|
| City |
Vancouver |
| State/province |
British Columbia |
| ZIP/Postal code |
V6T1Z3 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (16)
|
|
| Relations |
| BioProject |
PRJNA299027 |
| SRA |
SRP064923 |
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