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| Status |
Public on Oct 16, 2015 |
| Title |
ChIP-seq of the androgen receptor (AR) in MDAMB453 cells after androgen stimulation |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Serum starved MDAMB453 cells were serum starved and treated for 4 hours with vehicle control (ethanol), 5α-dihydrotestosterone (DHT; 10nM) or medroxyprogesterone acetate (MPA; 10nM). AR binidng peaks were determined. Subsequent analysis showed that binding sites for androgen receptor are enriched at breast cancer risk loci.
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| Overall design |
Each ChIP experiment was carried out in duplicate and consensus AR binding peaks were called. The conditions were vehcle (ethanol) treated, DHT and MPA stimulated cells.
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| Contributor(s) |
Hickey T, Campbell T, Meyer K |
| Citation(s) |
26618344 |
| |
| Submission date |
Oct 15, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Kerstin Meyer |
| Organization name |
University of Cambridge
|
| Department |
Cancer Research UK Cambridge Institute
|
| Street address |
Robinson Way
|
| City |
Cambridge |
| ZIP/Postal code |
CB2 0RE |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA298902 |
| SRA |
SRP064861 |
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