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Series GSE74069 Query DataSets for GSE74069
Status Public on Oct 16, 2015
Title ChIP-seq of the androgen receptor (AR) in MDAMB453 cells after androgen stimulation
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Serum starved MDAMB453 cells were serum starved and treated for 4 hours with vehicle control (ethanol), 5α-dihydrotestosterone (DHT; 10nM) or medroxyprogesterone acetate (MPA; 10nM). AR binidng peaks were determined. Subsequent analysis showed that binding sites for androgen receptor are enriched at breast cancer risk loci.
Overall design Each ChIP experiment was carried out in duplicate and consensus AR binding peaks were called. The conditions were vehcle (ethanol) treated, DHT and MPA stimulated cells.
Contributor(s) Hickey T, Campbell T, Meyer K
Citation(s) 26618344
Submission date Oct 15, 2015
Last update date May 15, 2019
Contact name Kerstin Meyer
Organization name University of Cambridge
Department Cancer Research UK Cambridge Institute
Street address Robinson Way
City Cambridge
ZIP/Postal code CB2 0RE
Country United Kingdom
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (7)
GSM1909086 MDA_MB_453_ARChIPseq_Vehicle1
GSM1909087 MDA_MB_453_ARChIPseq_Vehicle2
GSM1909088 MDA_MB_453_ARChIPseq_DHT1
BioProject PRJNA298902
SRA SRP064861

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Supplementary file Size Download File type/resource
GSE74069_AR_ChIP_DHT_4hrs_strigent_peaks.txt.gz 311.8 Kb (ftp)(http) TXT
GSE74069_AR_ChIP_MPA_4hrs_strigent_peaks.txt.gz 147.1 Kb (ftp)(http) TXT
GSE74069_AR_ChIP_Veh_4hrs_strigent_peaks.txt.gz 15.6 Kb (ftp)(http) TXT
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