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Series GSE72964 Query DataSets for GSE72964
Status Public on Jul 11, 2016
Title Tissue damage signals repurpose NF-κB, AP-1 and Smad3 to direct a Rev-erb sensitive wound healing program in macrophages
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary A complex damage signal promotes co-localization of NFκB and Smad3 at Rev-erb-sensitive enhancers and drives expression of genes characteristic of alternate polarization states in the same cells.
Overall design Chromatin mark H3K27Ac, transcription factors PU.1, cFos, SMAD3, and p65 were assessed by ChIP-Seq and RNA-Seq was used to measure gene expression in C57BL/6 and ReverbDKO mice and in in-vivo wounds
Contributor(s) Glass CK
Citation(s) 27462873
Submission date Sep 11, 2015
Last update date May 15, 2019
Contact name Christopher Glass
Phone 858-534-6011
Organization name University of California, San Diego
Department CMM
Lab Glass Lab
Street address 9500 Gilman Dr.
City La Jolla
State/province CA
ZIP/Postal code 92093
Country USA
Platforms (3)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
GPL19057 Illumina NextSeq 500 (Mus musculus)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (114)
GSM1875476 Sample1.H3K27Ac ChIP-Seq vehicle 6h
GSM1875477 Sample2.Input for H3K27Ac ChIP-Seq vehicle 6h
GSM1875478 Sample3.H3K27Ac ChIP-Seq tissue homogenate 6h
BioProject PRJNA295434
SRA SRP063628

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE72964_GeneExpression.txt.gz 4.1 Mb (ftp)(http) TXT
GSE72964_RAW.tar 7.1 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Processed data are available on Series record
Processed data provided as supplementary file
Raw data are available in SRA

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