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Series GSE72560 Query DataSets for GSE72560
Status Public on Sep 01, 2015
Title Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To identify the gene expression profile of enteric glia and assess the transcriptional similarity between enteric and extraenteric glia, we performed RNA sequencing analysis on PLP1-expressing cells in the mouse intestine. This analysis shows that enteric glia are transcriptionally unique and distinct from other cell types in the nervous system. Enteric glia express many genes characteristic of the myelinating glia, Schwann cells and oli- godendrocytes, although there is no evidence of myelination in the murine ENS.
Overall design Total RNA expression profiles of PLP1 expressing enteric glial cells (GFP+) and non-glial cells (GFP-negative) were obtained from the ileum and colon of juvenile PLP1-eGFP transgenic mice.
Contributor(s) Nelms B, Rao M
Citation(s) 26119414
Submission date Aug 31, 2015
Last update date Nov 22, 2022
Contact name Brad Nelms
Organization name University of Georgia
Street address 120 E Green St
City Athens
State/province GA
ZIP/Postal code 30602
Country USA
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (4)
GSM1865273 Ileal glia
GSM1865274 Non-glial ileal cells
GSM1865275 Colonic glia
BioProject PRJNA294325
SRA SRP063021

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Supplementary file Size Download File type/resource
GSE72560_Enteric_Glia.txt.gz 679.5 Kb (ftp)(http) TXT
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