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Status |
Public on Feb 10, 2016 |
Title |
Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes [ChIP-seq] |
Organism |
Homo sapiens |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
The molecular signature at histone H3K4 involved in epigenetic regulation of normal (MCF10A) and transformed (MCF7, MDA-MB-231) breast cells using ChIP-Seq technology. This study examines the dynamic distribution of H3K4me3 and H3K4ac histone modification associated with active chromatin to provide an understanding of the changes in epigenetic regulation associated with the unique breast cancer subtypes.
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Overall design |
H3K4me3 and H3K4ac histone modification study in normal (MCF10A) and transformed (MCF7, MDA-MB-231) breast cells using ChIP-Seq technology
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Contributor(s) |
Messier T, Boyd J, Stein G |
Citation(s) |
26783963 |
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Submission date |
May 29, 2015 |
Last update date |
Mar 04, 2022 |
Contact name |
Jonathan AR Gordon |
E-mail(s) |
Jonathan.A.Gordon@uvm.edu
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Organization name |
University of Vermont
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Department |
Biochemistry
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Street address |
89 Beaumont Ave Given E209
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City |
Burlington |
State/province |
VT |
ZIP/Postal code |
05405 |
Country |
USA |
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Platforms (1) |
GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
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Samples (18)
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This SubSeries is part of SuperSeries: |
GSE75169 |
Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes |
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Relations |
BioProject |
PRJNA285330 |
SRA |
SRP058852 |