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Series GSE69377 Query DataSets for GSE69377
Status Public on Feb 10, 2016
Title Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes [ChIP-seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The molecular signature at histone H3K4 involved in epigenetic regulation of normal (MCF10A) and transformed (MCF7, MDA-MB-231) breast cells using ChIP-Seq technology. This study examines the dynamic distribution of H3K4me3 and H3K4ac histone modification associated with active chromatin to provide an understanding of the changes in epigenetic regulation associated with the unique breast cancer subtypes.
 
Overall design H3K4me3 and H3K4ac histone modification study in normal (MCF10A) and transformed (MCF7, MDA-MB-231) breast cells using ChIP-Seq technology
 
Contributor(s) Messier T, Boyd J, Stein G
Citation(s) 26783963
Submission date May 29, 2015
Last update date Mar 04, 2022
Contact name Jonathan AR Gordon
E-mail(s) Jonathan.A.Gordon@uvm.edu
Organization name University of Vermont
Department Biochemistry
Street address 89 Beaumont Ave Given E209
City Burlington
State/province VT
ZIP/Postal code 05405
Country USA
 
Platforms (1)
GPL18460 Illumina HiSeq 1500 (Homo sapiens)
Samples (18)
GSM1700378 MCF10A_H3K4AC_R1
GSM1700379 MCF10A_H3K4AC_R2
GSM1700380 MCF10A_H3K4ME3_R1
This SubSeries is part of SuperSeries:
GSE75169 Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes
Relations
BioProject PRJNA285330
SRA SRP058852

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69377_MCF10A_H3K4AC_logFE.bw 942.3 Mb (ftp)(http) BW
GSE69377_MCF10A_H3K4ME3_logFE.bw 1.1 Gb (ftp)(http) BW
GSE69377_MCF7_H3K4AC_logFE.bw 1013.5 Mb (ftp)(http) BW
GSE69377_MCF7_H3K4ME3_logFE.bw 1.1 Gb (ftp)(http) BW
GSE69377_MDA231_H3K4AC_logFE.bw 1.1 Gb (ftp)(http) BW
GSE69377_MDA231_H3K4ME3_logFE.bw 976.6 Mb (ftp)(http) BW
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Raw data are available in SRA
Processed data are available on Series record

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