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Series GSE69346 Query DataSets for GSE69346
Status Public on Sep 30, 2015
Title An immediate transcriptional signature predicts response to the histone deacetylase inhibitor Givinostat in T acute lymphoblastic leukemia xenografts
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene expression analysis of three sets of patient-derived T-ALL xenografted murine lines treated or not treated with Givinostat, to investigate the immediate anti-leukemic effects after 6 hours of in vivo treatment with this histone deacetylase inhibitor.
 
Overall design Three different sets of class comparisons between Givinostat-treated and un-treated murine models xenografted with three different human primary pediatric T-ALL cells.
 
Contributor(s) Borga C, Pinazza M, te Kronnie G, Indraccolo S
Citation(s) 26764573
Submission date May 28, 2015
Last update date Mar 25, 2019
Contact name Chiara Borga
E-mail(s) chiaraborga@gmail.com
Organization name University of Padua
Street address Corso Stati Uniti,4
City Padova
ZIP/Postal code 35127
Country Italy
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (33)
GSM1698317 T-ALL_Patient_9_ Vehicle_1
GSM1698318 T-ALL_Patient_9_ Vehicle_2
GSM1698319 T-ALL_Patient_9_ Vehicle_3
Relations
BioProject PRJNA285332

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE69346_RAW.tar 150.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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