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| Status |
Public on May 21, 2015 |
| Title |
PTPRZ1 disruption-mediated gene expression changes in human glioblastoma stem cells [HG-U133_Plus_2] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Glioblastoma is the most aggressive and lethal malignant brain tumor. Gene expression profiling is useful in determining the genome-wide gene expression changes based on the experimental purpose. In order to interrogate the downstream targets of PTPRZ1, we applied gene expression profiles to screen the altered genes that are responsible for the functional phenotype changes. The results will provide a cue for mechanical analysis with potential translational values.
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| Overall design |
PTPRZ1-knocking down glioblastoma stem cells (GSCs) and control GSCs were used in this study. RNA were isolated using Primescript RT Master Mix (Takara). Profiling was established by applying Affymetrix GeneChip Human Genome U133 Plus 2.0 Array.
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| Contributor(s) |
Shi Y, Ping Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
May 18, 2015 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Yu Shi |
| E-mail(s) |
cadet_toutou@126.com
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| Organization name |
Institute of Pathology and Southwest Cancer Center
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| Department |
Southwest Hospital
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| Lab |
Key Laboratory of Tumor Immunopathology of Ministry of Education of China
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| Street address |
Gao-tan Yan Street
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| City |
Chongqing |
| State/province |
Chongqing |
| ZIP/Postal code |
400038 |
| Country |
China |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE69081 |
Gene expression profiles of PTPRZ1-knocking-down human glioblastoma stem cells |
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| Relations |
| BioProject |
PRJNA284495 |
