GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE68907 Query DataSets for GSE68907
Status Public on May 15, 2015
Title caArray_golub-00142: Gene expression correlates of clinical prostate cancer behavior
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Prostate tumors are among the most heterogeneous of cancers, both histologically and clinically. Microarray expression analysis was used to determine whether global biological differences underlie common pathological features of prostate cancer and to identify genes that might anticipate the clinical behavior of this disease. While no expression correlates of age, serum prostate specific antigen (PSA), and measures of local invasion were found, a set of genes was identified that strongly correlated with the state of tumor differentiation as measured by Gleason score. Moreover, a model using gene expression data alone accurately predicted patient outcome following prostatectomy. These results support the notion that the clinical behavior of prostate cancer is linked to underlying gene expression differences that are detectable at the time of diagnosis.
Overall design golub-00142
Assay Type: Gene Expression
Provider: Affymetrix
Array Designs: HG_U95Av2
Organism: Homo sapiens (ncbitax)
Citation(s) 12086878
Submission date May 14, 2015
Last update date Dec 13, 2018
Contact name Mervi Heiskanen
Phone 2402765175
Organization name NCI
Department CBIIT
Street address 9609 Medical Center Drive, 1W378
City Rockville
State/province MD
ZIP/Postal code 20850
Country USA
Platforms (1)
GPL8300 [HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array
Samples (102)
GSM1686235 golub-00142: N32_normal
GSM1686236 golub-00142: T50_tumor
GSM1686237 golub-00142: N01_normal
BioProject PRJNA283999

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE68907_RAW.tar 273.1 Mb (http)(custom) TAR (of CEL, TXT)
GSE68907_caArray_golub-00142.tar.gz 2.7 Mb (ftp)(http) TAR
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap