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| Status |
Public on Nov 10, 2015 |
| Title |
Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity [BAT] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of brown adipose tissue from Yin Yang 1 (YY1) brown fat specific knockout mice fed a high fat diet for 3 months. YY1 deficiency in brown adipose tissue leads to strong thermogenic deficiency. The goal was to identify the genes controlled by YY1 responsible of brown fat defective function.
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| |
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| Overall design |
Control mice YY1flox/flox versus YY1flox/flox; Ucp1Cre were fed a high fat diet for 3 months
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| |
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| Contributor(s) |
Verdeguer F, Puigserver P |
| Citation(s) |
26503783 |
| Submission date |
Apr 30, 2015 |
| Last update date |
May 04, 2018 |
| Contact name |
Francisco Verdeguer |
| E-mail(s) |
francisco_verdeguer@dfci.harvard.edu
|
| Organization name |
Dana Farber Cancer Institute
|
| Street address |
450 Brookline Ave
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE68443 |
Brown Adipose YY1 Deficiency Activates Expression of Secreted Proteins Linked to Energy Expenditure and Prevents Diet-Induced Obesity |
|
| Relations |
| BioProject |
PRJNA282723 |
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