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Series GSE67295 Query DataSets for GSE67295
Status Public on Feb 20, 2017
Title Inflammatory cytokines activate unliganded estrogen receptor and alter the sensitivity of breast cancer cells to tamoxifen
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary Genome-wide analyses of the transcriptomes and transcription factor recruitment in estrogen receptor breast cancer cells in response to estradiol, IL1b, or TNFa treatments. Also, the role of inflammatory cytokines on affecting tamoxifen sensitivity is analyzed on a genome-wide scale.
Overall design Transcription factor binding (ERa, p65) and transcriptome analyses were performed in estradiol- and pro-inflammatory cytokine-treated MCF7 cells.
Contributor(s) Glass CK
Citation(s) 28306507
Submission date Mar 25, 2015
Last update date May 15, 2019
Contact name Joshua D Stender
Organization name University of California at San Diego
Street address 9500 Gillman
City La Jolla
State/province CA
ZIP/Postal code 92093
Country USA
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (56)
GSM1643946 ERa ChIP-Seq Veh Rep1
GSM1643947 ERa ChIP-Seq Veh Rep2
GSM1643948 ERa ChIP-Seq E2 Rep1
BioProject PRJNA279424
SRA SRP056552

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE67295_GeneExpressionGroSeq.txt.gz 1.4 Mb (ftp)(http) TXT
GSE67295_GeneExpressionPolyA.txt.gz 2.7 Mb (ftp)(http) TXT
GSE67295_RAW.tar 4.6 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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