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| Status |
Public on Apr 13, 2016 |
| Title |
Differentially expressed genes after miRNA or siRNA transfection in human cancer cell lines (II) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To identify differentially expressed genes by anti cancer treatments (microRNAs or siRNAs) in human cancer, several cell lines (bladder cancer, prostate cancer, renal cell carcinoma, oral squamous cell carcinoma and lung squamous cell carcinoma) were subjected to Agilent whole genome microarrays.
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| Overall design |
Human cancer cell lines (SAS, HSC3, BOY, T24, PC3, PC3M, DU145, C4-2, 786-O, A-498 and EBC-1) were treated with miRNAs (miR-205, miR-29a, miR-144-3p, miR-144-5p, miR-451, miR-210, miR-145-5p, miR-145-3p, miR-23b cluster, miR-221, miR-222 and miR-223), siRNAs (si-GOLM1, si-HMGB3, si-CENPF, si-LOXL2, si-TMEM184B and si-CORO1C).
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| Contributor(s) |
Seki N |
| Citation(s) |
30153702, 27072587, 26057453 |
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| Submission date |
Mar 04, 2015 |
| Last update date |
Jul 31, 2019 |
| Contact name |
Naohiko Seki |
| E-mail(s) |
naoseki@faculty.chiba-u.jp
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| Phone |
+81-43-226-2971
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| Organization name |
Chiba University
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| Department |
Functional Genomics
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| Street address |
1-8-1, Inohana
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| City |
Chiba |
| State/province |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
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| Platforms (1) |
| GPL16699 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
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| Samples (32)
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| GSM1623420 |
Identification of miR-205 target genes in PC3 |
| GSM1623421 |
Identification of miR-205 target genes in DU145 |
| GSM1623422 |
Identification of miR-205 target genes in C4-2 |
| GSM1623423 |
Identification of miR-29a target genes in 786-O |
| GSM1623424 |
Identification of miR-29a target genes in A-498 |
| GSM1623425 |
Identification of miR-451 target genes in T24 |
| GSM1623426 |
Identification of miR-144-3p target genes in T24 |
| GSM1623427 |
Identification of miR-144-5p target genes in T24 |
| GSM1623428 |
Differentially expressed genes by knocking down of GOLM1-1 in PC3 |
| GSM1623429 |
Differentially expressed genes by knocking down of GOLM1-3 in PC3 |
| GSM1623430 |
Differentially expressed genes by knocking down of HMBG3-1 in PC3 |
| GSM1623431 |
Differentially expressed genes by knocking down of HMBG3-2 in PC3 |
| GSM1623432 |
Differentially expressed genes by knocking down of CENPF-1 in PC3 |
| GSM1623433 |
Differentially expressed genes by knocking down of CENPF-3 in PC3 |
| GSM1623434 |
Identification of miR-210 target genes in 786-O (24hours after reverse transfection) |
| GSM1623435 |
Identification of miR-210 target genes in 786-O (48hours after reverse transfection) |
| GSM1623436 |
Identification of miR-145-5p target genes in BOY |
| GSM1623437 |
Identification of miR-145-3p target genes in BOY |
| GSM1623438 |
Identification of miR-145-5p target genes in T24 |
| GSM1623439 |
Identification of miR-145-3p target genes in T24 |
| GSM1623440 |
Identification of miR-23b cluster target genes in 786-O |
| GSM1623441 |
Differentially expressed genes by knocking down of LOXL2-2 in 786-O |
| GSM1623442 |
Differentially expressed genes by knocking down of LOXL2-3 in 786-O |
| GSM1623443 |
Differentially expressed genes by knocking down of LOXL2-2 in A-498 |
| GSM1623444 |
Identification of miR-221 target genes in PC3 |
| GSM1623445 |
Identification of miR-222 target genes in PC3 |
| GSM1623446 |
Identification of miR-223 target genes in PC3 |
| GSM1623447 |
Identification of miR-223 target genes in PC3M |
| GSM1623448 |
Differentially expressed genes by knocking down of TMEM184B in SAS |
| GSM1623449 |
Differentially expressed genes by knocking down of TMEM184B in HSC3 |
| GSM1623450 |
Differentially expressed genes by knocking down of CORO1C-1 in EBC-1 |
| GSM1623451 |
Differentially expressed genes by knocking down of CORO1C-2 in EBC-1 |
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| Relations |
| BioProject |
PRJNA277164 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE66498_RAW.tar |
669.2 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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