|
| Status |
Public on Jun 30, 2015 |
| Title |
Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes [methylation] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
Examination of the genome-wide distribution of 5hmC in osteoarthritic chondrocytes compared to normal chondrocytes in order to elucidate the effect on OA-specific gene expression.
5hmC-sequencing was performed and data was compared with microarray gene expression data to identify genes with differential expression between normal and OA chondrocytes that are potentially under epigenetic regulation.
|
| |
|
| Overall design |
High-throughput sequencing of 5hmC in 4 normal and 4 OA chondrocyte samples.
|
| |
|
| Contributor(s) |
Taylor SE, Li YH, Wong WH, Bhutani N |
| Citation(s) |
25940674 |
| Submission date |
Dec 19, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Nidhi Bhutani |
| E-mail(s) |
nbhutani@stanford.edu
|
| Organization name |
Stanford University
|
| Department |
Orthopaedic Surgery
|
| Lab |
Bhutani
|
| Street address |
300 Pasteur Drive, R164 Edwards Bldg
|
| City |
Stanford |
| State/province |
California |
| ZIP/Postal code |
94305-5641 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (8)
|
|
| This SubSeries is part of SuperSeries: |
| GSE64395 |
Genome-wide mapping of DNA hydroxymethylation in osteoarthritic chondrocytes |
|
| Relations |
| BioProject |
PRJNA270885 |
| SRA |
SRP051399 |
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