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Series GSE64336 Query DataSets for GSE64336
Status Public on Dec 22, 2015
Title Expression data of worms under different caloric restriction mimetic treatments
Organism Caenorhabditis elegans
Experiment type Expression profiling by array
Summary We used microarray analysis to further our understanding of the mode of action of the well know caloric restriction mimetic rapamycin and the compound Allantoin first studied in the context of aging in this study. His work helps build on our understanding of potential caloric restriction mimetics predicted from our bioinformatic aproach of quering the Connectivity Map, a database of drug-induced gene expression profiles, using the transcriptional profile of CR to identify drugs that induce a similar or opposite gene expression profile.
 
Overall design Wild type worms of eat-2 mutants (a model of caloric restriction) were treated with the compounds of study with 2% DMSO or DMSO alone to serve as controls. All samples were peformed in triplicate.
 
Contributor(s) Calvert S, Tacutu R, De Magalhaes J
Citation(s) 26676933
Submission date Dec 18, 2014
Last update date Jul 06, 2016
Contact name João Pedro de Magalhães
E-mail(s) jp@senescence.info
Organization name The University of Liverpool
Department Institute of Integrative Biology
Street address Crown Street,
City Liverpool
ZIP/Postal code L69 7ZB
Country United Kingdom
 
Platforms (1)
GPL200 [Celegans] Affymetrix C. elegans Genome Array
Samples (15)
GSM1568724 Wild type worms treated with 2% DMSO alone replicate 1
GSM1568725 Wild type worms treated with 2% DMSO alone replicate 2
GSM1568726 Wild type worms treated with 2% DMSO alone replicate 3
Relations
BioProject PRJNA270762

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64336_RAW.tar 31.0 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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