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| Status |
Public on Jan 18, 2016 |
| Title |
RNA-seq of human fibroblasts during replicative senescence |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Senescent human fibroblasts were compared to young proliferating fibroblasts. Five different cell lines were compared. Illumina sequencing (HiSeq2000) was applied to generate 50bp single-end reads.
Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de)
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| |
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| Overall design |
48 samples: 3 biological replicates for each group: young proliferating and senescent BJ cells; young proliferating and senescent Wi-38 cells; young proliferating and senescent IMR-90 cells; 5 population doubling from young proliferating to senescent cell for HFF and MRC-5 cells
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| |
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| Contributor(s) |
Marthandan S, Klement K, Priebe S, Groth M, Platzer M, Hemmerich P, Diekmann S |
| Citation(s) |
26339636, 27140416 |
| |
| Submission date |
Nov 24, 2014 |
| Last update date |
Jul 18, 2019 |
| Contact name |
JenAge Project |
| E-mail(s) |
geo-data@jenage.de
|
| Organization name |
Leibniz Institute for Age Research - Fritz Lipmann Institute
|
| Street address |
Beutenbergstr. 11
|
| City |
Jena |
| ZIP/Postal code |
D-07745 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (48)
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| Relations |
| BioProject |
PRJNA268292 |
| SRA |
SRP050179 |
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