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Series GSE62442 Query DataSets for GSE62442
Status Public on Oct 01, 2015
Title Androgen receptor DNA binding in response to different ligands across three prostate cancer cell lines
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We performed AR ChIP-seq in LNCaP-AR, VCaP and CWR22PC cells in the presence of vehicle, androgen, or androgen plus antiandrogen. These three cell lines showed variable sensitivity to these drugs.
 
Overall design To determine the effects of AR agonist (R1881 vs DHT) and antagonists (Bicalutamide vs MDV3100) on the AR cistrome across a panel of prostate cancer cell lines.
 
Contributor(s) Cai L, Zheng D, Sawyers CL
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Submission date Oct 16, 2014
Last update date May 15, 2019
Contact name Yu Chen
E-mail(s) cheny1@mskcc.org
Phone 646-888-2163
Organization name Memorial Sloan Kettering Cancer Center
Department Human Oncology and Pathogenesis Program
Lab Chen
Street address 1275 York Ave, Box 20
City New York
State/province NY
ZIP/Postal code 10065
Country USA
 
Platforms (2)
GPL9442 AB SOLiD System 3.0 (Homo sapiens)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (15)
GSM1527022 LNCaP-AR_Input_DNA
GSM1527023 LNCaP-AR_Vehicle_AR_ChIP-seq
GSM1527024 LNCaP-AR_R1881_AR_ChIP-seq
This SubSeries is part of SuperSeries:
GSE62472 Cell context specific effect of AR antagonists on AR DNA binding and target gene expression
Relations
BioProject PRJNA264098
SRA SRP048997

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE62442_RAW.tar 1.3 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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