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| Status |
Public on Feb 01, 2015 |
| Title |
miRNA expression profiling of primary melanoma tumors (cohort I) |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
We performed global microRNA expression profiling of a cohort of primary melanoma patient samples linked to a well-annotated clinical database. The goal of this study was to identify microRNA that are associated to or correlated with various clinical parameters and patient outcomes. Candidate microRNA were identified for building prognostic models and functional testing.
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| Overall design |
92 primary melanoma (well-annotated with long clinical follow-up) and 9 congenital nevi samples were analyzed to Exiqon miRCURY two color arrays. The reference sample used was an equal combination of all samples analyzed. By this design, ratio data of test sample/reference is mean-centered data.
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| Contributor(s) |
Hernando E, Hanniford DS, Zhong J, Osman I |
| Citation(s) |
25677173, 26089374 |
| Submission date |
Oct 15, 2014 |
| Last update date |
Dec 16, 2015 |
| Contact name |
Eva Hernando-Monge |
| E-mail(s) |
Eva.Hernando-Monge@nyumc.org
|
| Phone |
212-263-9054
|
| Organization name |
NYU Langone Medical Center
|
| Street address |
550 1st Ave. Smilow 305
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10016 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19295 |
Exiqon miRCURY LNA array version 11.0 miRBASE version 14.0 |
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| Samples (101)
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| This SubSeries is part of SuperSeries: |
| GSE62372 |
miRNA expression profiling of primary melanoma tumors |
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| Relations |
| BioProject |
PRJNA263930 |
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