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| Status |
Public on Nov 01, 2014 |
| Title |
Genome-wide copy number and allele-specific copy number analysis of choroid plexus tumors (I) |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
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| Summary |
Copy number analysis was performed using genotyping microarrays for 55 choroid plexus tumors. Genomic aberrations were investigated by tumor histological classification and the pattern observed in each subgroup was further refined. Allele specific copy number analysis also allowed us to identify regions of acquired uniparental disomy with neutral copy number values.
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| Overall design |
Fifty-five choroid plexus tumors (23 choroid plexus carcinomas, 23 choroid plexus papillomas, 9 atypical choroid plexus papillomas) were used in this study. These samples were inspected for hybridization quality. No replicates were included.
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| Contributor(s) |
Merino DM, Shlien A, Villani A, Pienkowska M, Mack SC, Ramaswamy V, Shih DJ, Tatevossian R, Novokmet A, Choufani S, Dvir R, Ben-Arush M, Harris BT, Hwang EI, Lulla RR, Pfister SM, Achatz MI, Jabado N, Finlay JL, Weksberg R, Hawkins C, Taylor MD, Tabori U, Ellison DW, Gilbertson RJ, Malkin D |
| Citation(s) |
25336695 |
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| Submission date |
Aug 28, 2014 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Diana M Merino |
| E-mail(s) |
diana.merino@utoronto.ca
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| Organization name |
The Hospital for Sick Children
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| Department |
Genetics and Genome Biology
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| Lab |
Malkin
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| Street address |
686 Bay St.
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| City |
Toronto |
| State/province |
Ontario |
| ZIP/Postal code |
M5V0A4 |
| Country |
Canada |
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| Platforms (1) |
| GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
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| Samples (55)
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| This SubSeries is part of SuperSeries: |
| GSE60886 |
Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups |
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| Relations |
| BioProject |
PRJNA259772 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE60899_DMM-CPT-55GenomSeg-AlleleRatio.txt.gz |
182.4 Mb |
(ftp)(http) |
TXT |
| GSE60899_DMM-CPT-55GenomSeg-CopyNum.txt.gz |
325.8 Mb |
(ftp)(http) |
TXT |
| GSE60899_RAW.tar |
1.6 Gb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
| Processed data are available on Series record |
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