|
| Status |
Public on Dec 17, 2015 |
| Title |
The obese fetal transcriptome |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The objective of this study was to identify the tissue expression patterns and biological pathways enriched in term cord blood fetal RNA of obese women compared to lean
In fetuses of obese women, 683 differentially regulated genes were identified.
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| |
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| Overall design |
This was a prospective whole genome microarray study comparing umbilical cord blood samples collected from eight obese women and eight lean women at term who underwent prelabor cesarean delivery. A functional annotation tool was used to compare tissue expression patterns in cord blood samples from obese and lean women. Pathways analysis software identified physiological systems, molecular and cellular functions, and upstream regulators that were significantly differentially regulated in fetuses of obese women compared to lean.
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| |
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| Contributor(s) |
Edlow AG, Hui L, Wick HC, Bianchi DW |
| Citation(s) |
26840378 |
| |
| Submission date |
Aug 13, 2014 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Heather C Wick |
| E-mail(s) |
heather.c.wick@gmail.com
|
| Organization name |
Tufts University
|
| Department |
Department of Computer Science
|
| Street address |
161 College Ave
|
| City |
Medford |
| State/province |
MA |
| ZIP/Postal code |
02155 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA258194 |
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