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| Status |
Public on Jul 31, 2014 |
| Title |
Hypoxia-related Transcription factor ChIP-Seq data in T47D breast cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
We report the comprehensive genome-wide binding peaks for key factors inovled in oxygen sensing pathways, such as HIF1α, HIF1β and EglN2. In addition, we also report the genome-wide binding peaks for NRF1 in breast cancer cells
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| Overall design |
We conducted HA-EglN2, HIF1α, HIF1β (ARNT) or NRF1 ChIP-Seq in the T47D cell line that overexpresses HA-EglN2 in the presence of hypoxia (1%) and DMOG treatment. T47D parental cells treated with the same condition followed by HA ChIP-seq served as the control to filter non-specific binding.
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| Contributor(s) |
Zhang Q, Wang C |
| Citation(s) |
26492917 |
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| Submission date |
Jul 30, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Qing Zhang |
| E-mail(s) |
qing_zhang@med.unc.edu
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| Organization name |
University of North Carolina at Chapel Hill
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| Street address |
450 West Drive
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| City |
Chapel Hill |
| ZIP/Postal code |
NC 27599-7295 |
| Country |
USA |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (5)
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| This SubSeries is part of SuperSeries: |
| GSE59937 |
Hypoxia-related transcription factor ChIP-seq and EglN2 knockdown expression profiling in T47D breast cancer cells |
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| Relations |
| BioProject |
PRJNA257093 |
| SRA |
SRP045109 |