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Series GSE59935 Query DataSets for GSE59935
Status Public on Jul 31, 2014
Title Hypoxia-related Transcription factor ChIP-Seq data in T47D breast cancer cells
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We report the comprehensive genome-wide binding peaks for key factors inovled in oxygen sensing pathways, such as HIF1α, HIF1β and EglN2. In addition, we also report the genome-wide binding peaks for NRF1 in breast cancer cells
 
Overall design We conducted HA-EglN2, HIF1α, HIF1β (ARNT) or NRF1 ChIP-Seq in the T47D cell line that overexpresses HA-EglN2 in the presence of hypoxia (1%) and DMOG treatment. T47D parental cells treated with the same condition followed by HA ChIP-seq served as the control to filter non-specific binding.
 
Contributor(s) Zhang Q, Wang C
Citation(s) 26492917
Submission date Jul 30, 2014
Last update date May 15, 2019
Contact name Qing Zhang
E-mail(s) qing_zhang@med.unc.edu
Organization name University of North Carolina at Chapel Hill
Street address 450 West Drive
City Chapel Hill
ZIP/Postal code NC 27599-7295
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (5)
GSM1462475 T47D_HIF1α ChIP-seq
GSM1462476 T47D_HIF1β ChIP-Seq
GSM1462477 T47D_EglN2 ChIP-Seq
This SubSeries is part of SuperSeries:
GSE59937 Hypoxia-related transcription factor ChIP-seq and EglN2 knockdown expression profiling in T47D breast cancer cells
Relations
BioProject PRJNA257093
SRA SRP045109

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59935_RAW.tar 2.6 Mb (http)(custom) TAR (of BED)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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